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. 2019 Nov 6;15(11):e1007401. doi: 10.1371/journal.pcbi.1007401

Fig 10. HIV infection phenotype-specific predictions of PD-L1 blockade-mediated changes of virus load and CD4 T cell counts considering gains of HIV-specific CTL, HIV-infectible CD4 T cell targets and neutralizing antibodies.

Fig 10

Predictions based on the determined increases of HIV Gag-specific CD8 and CD4 T cells of infected donor 156 with an assumed 2-fold increase of neutralizing antibody titres are shown (predictions for the other donors are in S8 Fig). ΔV (open circles) refers to an absolute change in viral load. ΔCD4 (asterisks) indicates an increase in CD4 T cell numbers. μ, the fraction of restored activated CD4 T cells after PD-L1 blockade.