Table 4. Properties of the six pathways selected for the run-time analysis.
The number of genes (|V|), the number of edges (E), the cardinality of the largest clique (p*),the number of distinct hypothesis (m), and the number of permutations used for the computation of the permutation p-values (Np), for the six KEGG pathways highlighted in Fig 4. Pathway annotation is taken from the graphite Bioconductor package (version 1.24.1).
| Pathway name | |V| | E | p* | m | Np |
|---|---|---|---|---|---|
| 1. Arrhythmogenic right | 10 | 11 | 3 | 10 | 1000 |
| 2. Terpenoid backbone biosynthesis | 21 | 58 | 7 | 25 | 1000 |
| 3. Platinum drug resistance | 39 | 156 | 10 | 50 | 2000 |
| 4. Progesterone-mediated oocyte maturation | 87 | 338 | 18 | 101 | 4040 |
| 5. Apoptosis | 131 | 1014 | 27 | 200 | 8000 |
| 6. Proteoglycans in cancer | 202 | 1516 | 34 | 295 | 10000 |