Figure 8:

Left: Wu and Kofke overlap metrics between the end-states of $\Delta A_{(\mathrm{aq})}^{{\mathrm{MM}}^{\prime }\to \mathrm{QM}∕\mathrm{MM}}(A)$. Right: Wu and Kofke Π metrics. Each dot corresponds to one of the molecules in the solvation test set. The line passes through the mean value. The vertical bars are the standard deviation.