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. 2018 Jul 25;1(1):50–60. doi: 10.1021/acsptsci.8b00003

Figure 2.

Figure 2

SR9238 prevents alcohol induced fibrosis and lipid accumulation in rodent livers. (A) Representative images of PicoSirius Red stain showing marked difference in collagen staining with SR9238 treatment demonstrating SR9238’s ability to reduce and prevent alcohol induced hepatic fibrosis. %Collagen stained quantified using ImageJ (N = 6). (B) Representative images demonstrating how SR9238 treatment significantly reduces alcohol induced accumulation of neutral lipids in the liver, demonstrated by Bodipy 493/503 (N = 6). Images were quantified using ImageJ. ∗p < 0.05 and ∗ ∗ ∗ ∗p < 0.0001.