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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Orthop Res. 2019 May 17;37(9):1979–1987. doi: 10.1002/jor.24340

Figure 8.

Figure 8.

Analysis of key outcome measures in FLS from a set of healthy donors, treated for 6 days with IL-1α (IL-1), TNF-α (TNF), or cartilage wear particles (CWP), with untreated controls (CTL). Similar trends were observed in response to cytokine and particle treatment for monolayer content of DNA (a), and release of hyaluronan (b), inflammatory stress markers (eg. PGE2, c), cytokines (eg. IL-6, d), and MMPs (eg. MMP-1, e). N = 3 donors. *p < 0.05 vs. CTL. **p < 0.05 vs. CTL and CWP.