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. 2019 Oct 11;20(20):5049. doi: 10.3390/ijms20205049

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Administration of HCA suppressed CNV volume in mice. (A) Representative three-dimensional images of IB4-stained CNV. Individual CNV from each mouse was shown. (B) Quantification of the laser-induced CNV volume. Note that the administration of HCA significantly reduced the CNV volume when compared with the control group. Control: 278.05 ± 186 μm³, HCA 195.87 ± 107.57 μm³, n = 25, and 44 for control and HCA, respectively. Six and five mice for control and HCA, respectively. Control group: 25 CNV, six mice, HCA: 44 CNV, five mice, * p < 0.05.