Table 2. Univariate and multivariate cox regression analyses of OS and DFS in the TCGA group ccRCC patients.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	p-Value	HR (95% CI)	p-Value
Overall survival (OS)
Risk model (high/low)	1.10 (1.07-1.13)	2.13E-11	1.06 (1.03-1.10)	5.68E-06
Age	1.02 (1.01-1.04)	2.16E-05	1.02 (1.01-1.04)	6.03E-05
Gender	0.96 (0.70-1.31)	0.797
Histological grade	2.27 (1.85-2.78)	3.00E-15	1.47 (1.17-1.85)	0.000
Pathological stage	1.87 (1.64-2.13)	1.10E-20	1.65 (1.42-1.91)	6.06E-11
Disease free survival (DFS)
Risk model (high/low)	1.43 (1.23-1.66)	1.41E-06	1.28 (1.01-1.62)	0.033
Age	1.00 (0.99-1.02)	0.251
Gender	1.46 (0.97-2.18)	0.062
Histological grade	2.96 (2.28-3.82)	1.38E-16	1.68 (1.28-2.20)	0.000
Pathological stage	2.63 (2.21-3.14)	2.78E-27	2.33 (1.93-2.81)	9.84E-19