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. 2019 Oct 18;11(20):9060–9074. doi: 10.18632/aging.102374

Table 3. Impact of preoperative serum aminotransferase levels on 90-day mortality.

Death Patients Cumulative mortality Unadjusted Multivariable adjusted
No. No. Rate (95% CI) Hazard ratio (95% CI) Hazard ratio (95% CI)
ALT
 Low (≤13 IU/L) 77 1528 5.0 (3.9–6.1) 2.25 (1.65–3.08) 1.58 (1.14–2.18)†
 Middle (13–30 IU/L) 80 3512 2.3 (1.8–2.8) 1 (reference) 1 (reference)
 High (>30 IU/L) 26 1224 2.1 (1.3–2.9) 0.93 (0.60–1.45) 0.95 (0.60–1.49)
AST
 Low (≤17 IU/L) 46 1384 3.3 (2.4–4.3) 1.45 (1.02–2.08)* 1.31 (0.91–1.89)
 Middle (17–30 IU/L) 85 3687 2.3 (1.8–2.8) 1 (reference) 1 (reference)
 High (>30 IU/L) 52 1193 4.4 (3.2–5.5) 1.91 (1.35–2.70) 1.39 (0.96–2.01)
De Ritis ratio
 Low (≤0.85) 17 1274 1.3 (0.7–2.0) 0.57 (0.34–0.96)* 0.74 (0.44–1.25)
 Middle (0.85–1.62) 87 3745 2.3 (1.8–2.8) 1 (reference) 1 (reference)
 High (>1.62) 79 1245 6.3 (5.0–7.7) 2.79 (2.05–3.78) 1.59 (1.15–2.20)

*P<0.05, P<0.01, P<0.001.

SI conversion factors: To convert ALT and AST to μkat/L, multiply values by 0.0167.

ALT: alanine aminotransferase; AST: aspartate aminotransferase; CI: confidence interval.