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. 2019 Oct 24;11(20):9147–9166. doi: 10.18632/aging.102380

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Copyright © 2019 Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Altered functional connectivity within the DMN among the four groups. (A) Spatial distribution of the DMN (FWE correction). (B) Regions showing hypo- and hyperconnectivity within the DMN in the AD group; (C) Regions showing hypo- and hyperconnectivity within the DMN in the aMCI-m group; (D) Regions showing hypo- and hyperconnectivity within the DMN in the aMCI-s group. Abbreviations: DMN: default mode network; RSC: retrosplenial cortex; V1: primary visual cortex; MOG: middle occipital gyrus; PCC: posterior cingulate cortex; PCL: paracentral lobule; AG: angular gyrus; AD: Alzheimer's disease; aMCI-s: single-domain of amnestic mild cognitive impairment; aMCI-m: multiple-domain of amnestic mild cognitive impairment; NC: normal controls.