. 2019 Oct 24;11(20):9147–9166. doi: 10.18632/aging.102380

Table 1. Demographic and neuropsychological assessments of participants.

	AD (n = 20)	aMCI-m (n = 22)	aMCI-s (n = 29)	Normal controls (n = 23)	P Value
Age, mean (SD), y	70.84 (9.51)	71.09 (8.41)	71.21 (6.48)	64.61 (9.32) ^c	0.019^*
Sex, males/females	9/11	12/10	15/14	10/13	0.81^#
Education, mean (SD), y	7.47 (4.02) ^a	10.32 (3.72)	8.14 (3.89) ^a	11.43 (3.38)	0.002^*
AVLT scores, mean (SD)	12.68 (7.52) ^abc	29.50 (11.12) ^a	27.31 (5.87) ^a	48.96 (9.07)	< 0.001^*
BNT scores, mean (SD)	12.63 (6.78) ^abc	23.36 (2.15) ^ac	27.79 (1.35)	29.26 (0.86)	< 0.001^*
TMT scores, mean (SD)	259.79 (48.37) ^abc	114.09 (29.88) ^ac	79.52 (23.35)	71.04 (36.52)	< 0.001^*
MMSE scores, mean (SD)	16.58 (7.49) ^abc	24.45 (4.04) ^a	24.07 (3.47) ^a	28.61 (1.50)	< 0.001^*
MoCa scores, mean (SD)	12.11 (5.72) ^abc	20.36 (4.47) ^a	19.45 (4.24) ^a	26.65 (1.92)	< 0.001^*
CDT, (0, 1, 2, 3)	0 = 6, 1 = 7, 2 = 7 ^abc	1 = 6, 2 = 9, 3= 7 ^ac	2 = 5, 3 = 24	2 = 2, 3 = 21	< 0.001^#
CDR, (0, 0.5, 1-2)	0.5 = 1, 1-2 = 19 ^abc	0.5 = 22 ^a	0.5 = 29 ^a	0 = 23	< 0.001^#

Note: One-way ANOVA and Chi-square analyses were applied to test for group differences, statistical significance level was set at P < 0.05 (two-tailed). Significant P-values were in bold. Superscript letters indicated whether group mean was significantly worse than healthy controls (a), aMCI-m group (b) and aMCI-s group (c), based on post hoc pairwise comparisons (Bonferroni corrected P < 0.05). ^* The p value was obtained using One-way ANOVA. ^# The p value was obtained using Chi-square test with multiple comparison. Abbreviations: AVLT: Auditory Verbal Learning Test; BNT: Boston Naming Test; TMT: Trail-Making Test; MMSE: Mini-Mental State Examination; MoCa: Montreal Cognitive Assessment; CDT: Clock-Drawing Test; CDR: Clinical Dementia Rating; AD: Alzheimer's disease; aMCI-m: Multiple-Domain Amnestic Mild Cognitive Impairment; aMCI-s: Single-Domain Amnestic Mild Cognitive Impairment.