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. 2019 Oct 17;11(20):8845–8859. doi: 10.18632/aging.102300

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Copyright © 2019 Long et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The differentially expressed mRNAs and pathway in PA. (A) Volcano plot of differentially expressed genes in the whole cohort vs. normal. The red dots represent up-regulated genes and the green dots represent down-regulated genes; (B) Heatmap of top ten differentially expressed genes in tumor vs. normal; (C) The dotplot of significantly altered pathways in PA tissues analyzed by GSEA; (D) The heat map of differentially expressed mRNAs in the PI3K-Akt pathway analyzed from microarray GSE26966; (E) The correlative network of COL6A6 and differentially expressed mRNAs involved in the PI3K-Akt signaling pathway in PA.