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. 2019 Oct 15;11(10):6600–6618.

Figure 3.

Figure 3

LINC01234 affects cycle progression and apoptosis of MM cells. A. Cell cycle analysis of RPMI-8226 or U266 cells after transfecting with siRNAs for si-LINC01234 (si-LINC01234 2#, si-LINC01234 3#) or the corresponding control (si-NC). Cell percentage in G1, S and G2 phages were quantified and shown as histograms (One-way ANOVA). B. Cell apoptosis analysis of RPMI-8226 or U266 cells after transfecting with siRNAs for LINC01234 (si-LINC01234 2#, si-LINC01234 3#) or the corresponding control (si-NC). Apoptosis rates were quantified and shown as histograms (One-way ANOVA). C. The protein levels of p21, CDK4, p27, Bcl-2, Bax and Cleaved caspase3 in RPMI-8226 or U266 cells after transfecting with siRNAs for LINC01234 (si-LINC01234 2#, si-LINC01234 3#) or the corresponding control (si-NC), using western blotting. Relatively quantitative results was determined by Image J and shown as histogram (One-way ANOVA). The data are expressed as mean ± SEM, *P < 0.05; **P < 0.01; ***P < 0.001.