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. 2019 Oct 31;9:1079. doi: 10.3389/fonc.2019.01079

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Copyright © 2019 Zhang, Peng, Huang, Lin, Zhou and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Western blotting on protein expressions of ERα, GPR30, EGFR, pEGFR, ERK, and pERK. (A) Protein expression in Ishikawa and HEC-1B cells with or without exposure to 10 μM BDE-47. (B) Protein expression in Ishikawa-BDE-47 and HEC-1B-BDE-47 cells treated with or without siERα, and siGPR30. (C) Expression of pEGFR and EGFR in Ishikawa-BDE-47 and HEC-1B-BDE-47 after pEGFR inhibitor (erlotinib) treatment (left). Expression of pERK and total ERK in Ishikawa-BDE-47 and HEC-1B-BDE-47 after pERK inhibitor (DP98059) treatment (right).