Table 2.

Nanoparticle pharmacokinetic properties.

Particle	Distribution Half-life (t1/2,dist)51	Kel,dist [min−1]	Elimination Half-life (t1/2,elim)51	Kel,elim [min−1]	Area under concentration-time curve (AUC)
Cj-1	4.74 ± 1.58	0.16 ± 0.055	29.69 ± 2.53	0.024 ± 0.002	152 ± 59 [min mg mL−1]
PLGA	3.12 ± 1.33	0.25 ± 0.068	44.02 ± 14.23	0.017 ± 0.005	329 ± 130 [min mg mL−1]
Pro-NP	3.64 ± 1.79	0.23 ± 0.11	27.74 ± 10.19	0.029 ± 0.012	6116 ± 3200 [min mg mL−1]
Gd-DTPA	4.01 ± 2.47	0.23 ± 0.11	15.70 ± 8.50	0.056 ± 0.023	6.6 ± 3.8 [min mM]