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. 2019 Nov 6;9:16158. doi: 10.1038/s41598-019-52570-2

Table 3.

Short- term outcomes (at 2 months).

Encephalitis (n = 20) Aseptic meningitis (n = 46) p-value
Time to follow-up, daysb 79 (60) 62 (44) 0.048
No reported complaints (%) 1/20 (5) 17/46 (37) 0.007
Sick leave, total no (%) 12/12 (100) 16/43 (37) <0.001
  100% unable to work (%) 7/12 (58) 5/43 (12) 0.002
GOSE
GOSE <4 1 (5) 0 0.007
GOSE = 5–6 14 (74) 18 (39)
GOSE = 7–8 4 (21) 28 (61)
SF-36 subscores a
Physical functioning (PF) 78.5 (21) 89.3 (18) ns
Role physical (RP) 16.2 (32) 45.2 (48) 0.01
Role emotional (RE) 58.8 (42) 77.4 (38) ns
Bodily pain (BP) 68.9 (28) 65.7 (25) ns
General health (GH) 61.8 (21) 66.6 (27) ns
Vitality (VT) 45 (15) 51.1 (23) ns
Social functioning (SF) 61.8 (26) 71.1 (31) ns
Mental health (MH) 73.2 (14) 79.2 (15) ns
Physical component summary (PCS) 43.6 (8) 46.7 (10) ns
Mental component summary (MCS) 45 (8) 49 (11) ns
HAD
HAD sum A, median
Sum 0–7, no of patients (%) 15 (88) 34 (79) ns
Sum 8–10, no of patients (%) 1 (6) 5 (12) ns
Sum 11–21, no of patients (%) 1 (6) 4 (9) ns
HAD, sum D, median ns
Sum 0–7, no of patients (%) 16 (94) 40 (93) ns
Sum 8–10, no of patients (%) 1 (6) 2 (5) ns
Sum 11–21, no of patients (%) 0 1(2) ns
Reported subjective complaints
Headache (%) 6/20 (30) 23/46 (50) ns
Neck stiffness (%) 0 4/44 (9) ns
Photophobia (%) 7/18 (39) 8/46 (17) ns
Phonophobia (%) 7/18 (39) 12/46 (26) ns
Neurological symptomsc (%) 13/20 (65) 11/46 (24) 0.001
Concentration difficulties (%) 12/20 (60) 13/46 (28) 0.015
Memory problems (%) 14 /20 (70) 17/46 (37) 0.013
Emotional changed (%) 7/18 (39) 13/46 (28) ns
Extensive tiredness (%) 15/20 (75) 18/46 (39) 0.007
Sleep disturbancee (%) 14/20 (70) 14/46 (30) 0.003

Data are presented as number of patients (%), amean (SD) or bmedian (IQR). cMost reported were difficulty finding words, reduced coordination, urinary retention. dFeeling of anxiousness or mood disorder, eincreased need of sleep. GOSE: Glasgow Outcome Scale Extended, SF-36: Survey Short Form, HAD: Hospital Anxiety and Depression Scale.