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. 2019 Nov 6;9:16130. doi: 10.1038/s41598-019-52513-x

Figure 6.

Figure 6

Ferroptotic pathway gene enrichment analysis based on the KEGG database. DEGs were labeled into the map of ferroptosis pathway obtained from KEGG database with official permission and guidance57–59. (A) DEGs between the control and 10 µM dexamethasone treatment groups were enriched in the KEGG ferroptotic pathway based on 2 biological replicates. The downregulated genes are labelled with green, and the upregulated genes are labelled with red. (B) DEGs between 10 µM dexamethasone and the 10 µM dexamethasone + 100 µg EPC-EV treatment groups were enriched in the KEGG ferroptotic pathway based on 2 biological replicates. The downregulated genes are labelled with green, and the upregulated gene are labelled with red.