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. 2019 Nov 6;9:16151. doi: 10.1038/s41598-019-51651-6

Table 1.

Risks for in situ and invasive cancer when family members were diagnosed with concordant in situ or invasive cancer.

Cancer site family member RR for in situ cancer when family had the same in situ cancer RR for invasive cancer when family had same in situ cancer RR for in situ cancer when family had the same invasive cancer
Cases RR 95%CI Cases RR 95%CI Cases RR 95%CI
Cervix 20188 1.77 1.75–1.80 1127 1.41 1.33–1.50 2763 1.54 1.48–1.60
Other female genital 15 2.74 1.65–4.56 4 1.19 0.45–3.18 9 1.06 0.55–2.05
Skin squamous cell 3207 2.29 2.21–2.38 1620 1.92 1.83–2.02 2097 2.07 1.98–2.17
   Male 1612 2.30 2.19–2.42 951 1.96 1.83–2.10 1047 2.08 1.95–2.21
   Female 1595 2.28 2.17–2.40 669 1.87 1.73–2.03 1050 2.07 1.95–2.21

RR = relative risk, 95%CI = 95% confidence interval, bold font indicates that the lower limit of 95%CI does not include 1.00.