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. 2019 Aug 22;411(26):6847–6856. doi: 10.1007/s00216-019-02052-1

Table 2.

Comparison of three different brain regions of interest in WKY and SHRSP rats

Hippocampus Striatum Hypothalamus
Peak intensity Ratio Peak intensity Ratio Peak intensity Ratio
mTRAQΔ0 GABA mTRAQΔ4 GABA mTRAQΔ4 GABA mTRAQΔ4 GABA mTRAQΔ0 GABA mTRAQΔ4 GABA
WKY no. 1 580,921 1,464,578 0.40 1,036,339 1,655,661 0.63 1,828,763 1,660,663 1.10
WKY no. 2 857,537 1,999,239 0.43 1,114,299 1,865,746 0.60 2,044,267 2,058,933 0.99
WKY no. 3 906,989 2,072,277 0.44 1,053,054 1,864,875 0.56 2,585,214 2,305,500 1.12
SHRSP no. 1 317,071 1,533,812 0.21 371,867 1,717,641 0.22 1,687,085 2,511,636 0.67
SHRSP no. 2 429,512 1,688,049 0.25 175,346 521,826 0.34 464,130 680,984 0.68
SHRSP no. 3 476,865 2,093,849 0.23 706,273 2,808,847 0.25 2,113,803 3,179,151 0.66
Region of interest Ratio CV (%) p value
WKY SHRSP WKY SHRSP
Hippocampus 0.42 ± 0.02 0.23 ± 0.02 5.1 10.4 0.00050
Striatum 0.60 ± 0.03 0.27 ± 0.06 5.1 22.9 0.00117
Hypothalamus 1.07 ± 0.07 0.67 ± 0.01 6.4 1.2 0.00058

Ratio value was calculated by peak intensities of mTRAQΔ0 GABA to mTRAQΔ4 GABA in each part and represented as mean ± SD (n = 3)