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. Author manuscript; available in PMC: 2019 Nov 7.
Published in final edited form as: Ann N Y Acad Sci. 2019 May 10;1455(1):196–205. doi: 10.1111/nyas.14098

Figure 1.

Figure 1.

BDPP treatment produces antidepressant effects in both naive and stressed mice. (A) Timeline of chronic BDPP treatment, chronic variable stress and behavioral tests. (B) BDPP treatment did not affect the locomotor activity in naive and stressed mice (C) BDPP treatment significantly increased grooming time in the SST in naive mice and averted reduction in grooming time in stressed. (D) BDPP treatment significantly decreased immobility time in the FST in naive mice and averted increase in immobility time in stressed mice, n = 9 ~ 13 per group. All data are presented as mean ± s.e.m. Two- way analysis of variance followed by Fisher’s LSD test for B-D (* P < 0.05). OFT open field test, SST sucrose splash test, FST forced swim test.