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. Author manuscript; available in PMC: 2020 Nov 5.
Published in final edited form as: Anal Chem. 2019 Oct 16;91(21):13528–13537. doi: 10.1021/acs.analchem.9b02620

Figure 1.

Figure 1.

(a) Electropherogram of N-glycans released from human urinary exosomes, methylamidated, labeled with APTS, and separated by microfluidic CE with LIF detection. Large tetra-antennary N-glycan compositions were detected with migration times >135 s and were quite abundant. (b) N-Glycans released from urinary exosomes were fractionated on the basis of their charge states by ion-exchange chromatography, methylamidated, labeled with APTS, and separated by microfluidic CE. Structures were assigned to the electropherograms by correlating migration time and peak area with mass and relative abundance of glycans detected by MALDI-MS.