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. 2018 Oct 1;198(7):903–913. doi: 10.1164/rccm.201712-2472OC

Figure 2.

Figure 2.

Receiver operating characteristic curves for SeptiScore, calculated for the complete clinical dataset. (A) Receiver operating characteristic curves. Unanimous retrospective physician diagnosis (RPD) (nsepsis = 121; nSIRS = 171; nexcluded = 155; area under the curve [AUC], 0.89; 95% confidence interval [CI], 0.85–0.93), consensus RPD (nsepsis = 180; nSIRS = 230; nexcluded = 37; AUC, 0.85; 95% CI, 0.81–0.89), and forced RPD (nsepsis = 202; nSIRS = 245; AUC, 0.82; 95% CI, 0.78–0.86). (B) Sensitivity, specificity as a function of cut point. Comparator = consensus RPD. The following SeptiScore band boundaries are indicated: band 1/2 boundary at 3.05, band 2/3 boundary at 4.45, and band 3/4 boundary at 5.95, as well as the Youden index (Y) at 5.1 (when sensitivity + specificity is maximized). SIRS = systemic inflammatory response syndrome.