Table 2.

Summary of studies included in the systematic review that investigated the effect of CrM plus HMB on body composition.

Author/s	Population	Intervention	Outcomes	Effects
				CrM+HMB Vs CON/PLG	CrM+HMB Vs CrMG	CrM+HMB Vs HMBG
Jówko et al., (2001) [36]	40 healthy males (21.0 ± 2.1 years)	Randomized, double-blind, placebo-controlled CrM: 20 g/day (first 1 week) + 10 g/day (2 weeks) HMB: 3 g/day Duration: 3 weeks	BM BF LBM	BM FM LBM	BM FM LBM	BM FM LBM
O’Connor & Crowe (2007) [40]	30 male elite rugby players (24.9 ± 1.5 years)	Controlled CrM: 3 g/day HMB: 3 g/day Duration: 6 weeks	BM Sum of six skinfolds Arm girth (relaxed) Arm girth (fixed) Chest girth Waist girth Hip girth Thigh girth Femur diameter Humerus diameter	BM Sum of six skinfolds Arm girth (relaxed) Arm girth (fixed) Chest girth Waist girth Hip girth Thigh girth Femur diameter Humerus diameter	No data showed	BM Sum of six skinfolds Arm girth (relaxed) Arm girth (fixed) Chest girth Waist girth Hip girth Thigh girth Femur diameter Humerus diameter
Zajac et al., (2003) [37]	52 well trained basketball players (25.6 ± 5.6 years)	Randomized, placebo- controlled CrM: 15 g/day (first 5 days) + 5 g/day (rest of the days) HMB: 3 g/day Duration: 30 days	BM FFM FM	↑ BM ↑ FFM ↓ FM	BM FFM ↓ FM	↑ BM ↑ FFM FM

CrM: Creatine monohydrate supplementation, HMB: HMB supplementation, CON/PLG: Placebo or control group, HMBG: HMB supplementation group, CrMG: Creatine monohydrate supplementation group, LBM: Lean body mass, BM: Body mass, FM: Fat mass, FFM: Fat free mass; ↑: Increase, ↓: Decrease, : No effect.