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. 2019 Oct 14;17(10):583. doi: 10.3390/md17100583

Figure 3.

Figure 3

(A) Sequence comparison among the six sC1q-like type 2 paralogous genes LOC111105959, LOC111105960, LOC111105962, LOC111106427, LOC111106428 and LOC111109313, all found in chromosome 8. Identity percentages are shown for exon1, intron 1 and exon 2 separately, using the LOC111106428 sequence as a reference. Sequence conservation is shown with a heat map and indels are shown as line breaks. (B) Position of sites subject to positive selection in the six largest clusters of paralogous C1qDC genes identified in C. virginica. Strongly supported sites (i.e., detected with at least 2 different prediction methods) are shown in red. Sites with moderate support (i.e., detected with just one prediction method) are shown in yellow. The position of the beta strands in the human C1q chain A (PDB: 1PK6) are indicated by blue blocks.