Figure 3.

Effect of endothelial nitric oxide synthase (eNOS) inhibition via L-NAME on FID and AchID in adipose tissue resistance arterioles collected on the day of surgery (n = 15 subjects). FID measurements corresponding to intraluminal pressure gradients of 10–100 cm H₂O in VAT arterioles (A) and SAT arterioles (C) with and without vitamin D incubation. AchID measurements corresponding to increasing Ach concentrations (10⁻⁹ to 10⁻⁴ M) in VAT arterioles (B) and SAT arterioles (D) with and without vitamin-D incubation. All measurements are presented as means ± standard error (SE); ₸ p < 0.05 comparing L-NAME with baseline, † p < 0.05 comparing vitamin D with baseline, and * p < 0.05 comparing L-NAME + vitamin D with vitamin D alone.