Figure 4.

(A) (a) Schematic illustration of synthetic procedure and pH-responsive DOX release, (b) TEM image of MgAl-LDH-DOX, (B) (a) pH-responsive DOX release profiles from MgAl-LDH-DOX in PBS at 37 °C, (b) in vivo fluorescence images of H22 tumor-bearing mice at different time courses after intravenous injection of free Cy5 or Cy5-MgAl-LDH at the Cy5 dose of 0.3 mg/kg, respectively, (c) intracellular DOX content in HepG2 cells treated with free DOX or MgAl-LDH-DOX at DOX concentration of 3 μg/mL for different time intervals by flow cytometry, reproduced from [23], with permission from the Royal Society of Chemistry, 2018.