Table 1.
Cytotoxic activity of different fermentation conditions against three different cancer lines (HepG2, Miapaca2 and MCF-7). Cell proliferation inhibition percentage values in negative and cell overgrowth percentage values in positive.
Fermentation Condition (n = 10) | HepG2 (%) ( ± SD) | MCF-7 (%) ( ± SD) | MiaPaca2 (%) ( ± SD) |
---|---|---|---|
MMK2 | −13 ± 15 | −16 ± 19 | −17 ± 23 |
MMK2+ XAD-16 | −100 ± 0 | −100 ±2 | −92 ± 24 |
MMK2+ 5-azacytidine | −31 ± 11 | −55 ± 22 | −63 ± 11 |
MMK2+ hydralazine | 13 ± 2 | −6 ± 4 | −27 ± 6 |
MMK2+ quercetin | −5 ± 9 | −19 ± 7 | −31 ± 11 |
MMK2+ SBHA | −29 ± 14 | −34 ±1 6 | 7 ± 7 |
MMK2+ sodium butyrate | 2 ± 16 | 2 ± 11 | 1 ± 8 |
MMK2+ valproic acid | −100 ± 0 | −100 ± 1 | −100 ± 28 |
Highlighted in bold are conditions that showed a cell proliferation inhibition higher than 50%.