Table 1.
Characterization of drug-loaded polymeric nanoparticles (NPs).
| Samples (n = 3) | Size (d.nm) | PDI | ZP (mV) | DTX LC (%) | DOX LC (%) |
|---|---|---|---|---|---|
| DTX/NPs | 105.3 ± 2.3 | 0.128 | −21.5 ± 4.7 | 9.88 ± 0.41 | N.A. |
| DTX/NPs@PDA | 161.5 ± 3.6 | 0.151 | −17.3 ± 5.1 | 9.67 ± 0.39 | N.A. |
| DTX/NPs@PDA-PEG | 166.3 ± 4.1 | 0.139 | −13.6 ± 3.8 | 9.43 ± 0.43 | N.A. |
| DTX/NPs@PDA-PEG-Apt | 167.1 ± 3.9 | 0.145 | −13.4 ± 4.1 | 9.39 ± 0.32 | N.A. |
| DTX/NPs@PDA/DOX-PEG-Apt | 170.3 ± 4.6 | 0.160 | −10.6 ± 2.9 | 8.47 ± 0.27 | 8.61 ± 0.34 |
PDI: polydispersity index; ZP: zeta potential; LC: loading content; N.A.: not applicable.