Table 1.
First Author, Year | Target Age (Months) | Intervention Group 1 | Control Group | Intervention Duration (Months) | Age When Outcomes Measured (Months) | Outcomes Measured 2 |
---|---|---|---|---|---|---|
Shuhua Ni, 1995 [22] | 5–13 | 2 counties; n = 76; YYB-C |
2 counties; n = 77; Blank control |
8 months | 13 | Height, weight, Kaup index, Vervaeck index, urine hydroxyproline index |
Yuying Wang, 2004 [10] | 4–12 | 5 counties; n = 670; YYB-B |
5 counties; n = 307; Energy matched rice flour |
12 months | 16–24 | Hb concentration and prevalence of anemia |
Yuying Wang, 2006 [23] | 4–12 | 5 counties; n = 232; YYB-B |
5 counties; n = 116; Energy matched rice flour |
Until 24 months of age for each child | 24 | Developmental quotient |
Dongmei Yu, 2007 [24] | 4–12 | 5 counties; n = 978; YYB-B |
5 counties; n = 500; Energy matched rice flour |
12 months | 16–24 | Prevalence of diarrhea and respiratory infection in past two weeks |
Yuying Wang, 2007 [25] | 4–12 | 5 counties; n = 978; YYB-B |
5 counties; n = 500; Energy matched rice flour |
Until 24 months of age | 24 | WAZ, HAZ |
Yuying Wang, 2009 [26] | 6–12 | 5 counties; n = 978; YYB-B |
5 counties; n = 500; Energy matched rice flour |
12 months | 18–24 | Hb concentration and prevalence of anemia |
Chunming Chen, 2010 [27] | 4–12 | 5 counties; n = 232; YYB-B |
5 counties; n = 116; Energy matched rice flour |
Until 24 months of age | 24 | Development quotient, intelligent quotient |
Zhifeng Fang, 2010 [28] | 6–24 | 3 counties; n = 146; YYB-A |
3 counties; n = 107; Blank control |
6 months | 12–30 | Prevalence of stunting, underweight, wasting and anemia |
China Development and Research Foundation, 2011 [29] | 6–24 | 6 counties; n = 1034; YYB-A |
6 counties; n = 449; Blank control |
24 months | 24–36 | Prevalence of underweight, stunting and wasting, Hb concentration and anemia prevalence |
Wenli Zhao, 2012 [30] | 0–60 | 2 counties; n = 676; YYB-A |
2 counties; n = 536; Blank control |
12 months | 12–72 | Height, weight, prevalence of stunting, underweight and wasting, Hb concentration and prevalence of anemia |
Songli Fan, 2013 [31] | 6–24 | 27 counties; n = 113; YYB-A |
27 counties; n = 328; Blank control |
3 months | 9–27 | Hb concentration and prevalence of anemia |
Wenhao Li, 2013 [32] | 4–30 | 3 counties; n = 146; YYB-A |
3 counties; n = 146; Blank control |
3 months | 7–33 | Height, weight, anemia prevalence, and Hb concentration |
Lingyun Ren, 2013 [33] | 6–11 | One county; n = 76; YYB-A |
One county; n = 78; Blank control |
Until 24 months of age for each child | 24 | Height, weight, WAZ, HAZ, prevalence of stunting, underweight and wasting, Hb concentration and prevalence of anemia |
Shangming Li, 2014 [34] | 0–36 | One county; n = 387; YYB-A |
One county; n = 240; Blank control |
Until 36 months of age for each child | 36 | Prevalence of stunting, underweight and anemia |
Qin Hu, 2016 [35] | 6–36 | One county; n = 589; YYB-A |
One county; n = 300; Blank control |
6 months | 12–42 | Height, weight, head circumference, Hb concentration and prevalence of anemia and rickets |
Xiaoting Ding, 2016 [36] | 6–18 | 3 counties; n = 483; YYB-A |
3 counties; n = 248; Blank control |
6 months | 12–24 | Height, weight, WAZ, HAZ, WHZ, Hb concentration, prevalence of underweight, wasting, stunting and anemia |
Yanfeng Zhang, 2016 [7] | 6–23 | One county; n = 2186; YYB-A |
One county; n = 760; Blank control |
Until 24 months of age for each child | 6–23 | Prevalence of stunting and anemia |
Shuai Li, 2017 [37] | 6–24 | One county; n = 450; YYB-A |
One county; n = 450; Blank control |
12 months | 18–36 months | Height, weight, WAZ, HAZ, WHZ, Hb concentration, prevalence of underweight, wasting, stunting and anemia |
1 Composition of YYB-A, B, C presented in Table S1. 2 Abbreviations: YYB, Yingyangbao; T, intervention group; C, control group; WAZ, weight-for-age z score; HAZ, height-for-age z score; WHZ, weight-for-height z score; Hb, hemoglobin.