Figure 9.
Effect of water extract (CLW) from Curcuma longa L. on activation of AMPK and ACC in high-fat diet-fed mice. (A) 5′ adenosine monophosphate-activated protein kinase (AMPK) and phosphorylation of acetyl-coenzyme A carboxylase (ACC) protein levels were monitored by Western blot analysis. (B) and (C) Protein density of ACC and AMPK. CON, normal control diet; HF, 60% high-fat diet; C-LOW, 60% high-fat diet plus 300 mg/kg b.w./day of CLW; C-HIGH, 60% high-fat diet plus 900 mg/kg b.w./day of CLW; SILY, 60% high-fat diet plus 50 mg/kg b.w./day of silymarin. Data are expressed as mean ± S.E. (n = 10), and different letters indicate significant differences (p < 0.05), as determined via Duncan’s multiple range test.