UVB-induced damage of normal human foreskin fibroblast (Hs68) was decreased by pretreatment with fermented blackberry (FBB). Cells were treated with various doses of L. plantarum JBMI F5 (LP), BB inoculated with L. plantarum JBMI F5 blackberry (BBL), and FBB for 24 h. Cytotoxicity was determined with MTT assay. The cell survival activity for cells with pretreated with different concentrations of LP, BB, BBL, and FBB for 24 h and irradiated with UVB (100 mJ/cm2) in Hs68 cells. The viability was analyzed using MTT assay. *** p < 0.001 vs. Blank; #
p < 0.05, ##
p < 0.01, ###
p < 0.001 vs. Control (CON, UVB irradiated group). Bar; Cell viability, Line; Cytotoxicity. Values are means ± SEM of three independent experiments.