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. 2019 Oct 22;9(10):1501. doi: 10.3390/nano9101501

Figure 10.

Figure 10

Carbon nanotube (CNT)-based delivery systems for peptides and proteases. (A) SEM images of calcium phosphate cement (CPC)–MWCNT–Z-Leu-Leu-Leu-al (MG132). (B) The luciferase assay shows that MG132 released from CPC or CPC–MWCNT inhibited TNF-α-induced NF-κB activation and osteoclast differentiation. (C) Schematic diagram of CNT–poly(lactide-co-glycolide) (PLGA) conjugate fabrication and cell-to-cell delivery. (D) Penetration of CNT–PLGA–proteins into osteosarcoma cells cultured in CNT–PLGA–fBSA (fluorescent bovine serum albumin) (a,b) and CNT–PLGA–BSA penetrating the osteosarcoma cell (c,d). Reproduced with permission from [230,233]. Elsevier, 2014; PLOS: Open Access, 2013.