. 2019 Oct 10;11(10):2418. doi: 10.3390/nu11102418

Table 6.

The effect of the intervention with iron supplementation on Stratum 2 (0:40 mg/d, 1:20 mg/d) throughout pregnancy regarding maternal iron status in the third trimester, according to initial iron stores.

SF < 15 µg/L
Serum ferritin levels	β	SE	p	Model
Crude model	−0.24	0.14	0.083	R² = 0.061 p = 0.083
^b Adjusted model	−0.39	0.15	0.014	R² = 0.344 p = 0.021
Iron deficiency (0:no, 1:yes)	OR	95% CI	p	Model
Crude model	6.11	0.60–62.23	0.126	R² Nagelkerke = 0.163 p = 0.085
^b Adjusted model	42.09	0.00–50.00	0.614	R² Nagelkerke = 0.924 p = 0.001
SF ≥ 15 µg/L
Hemoglobin levels	β	SE	p	Model
Crude model	–1.75	1.54	0.260	R² = 0.002 p = 0.260
^a Adjusted model	–2.00	1.56	0.200	R² = 0.184 p < 0.001
Serum ferritin levels	β	SE	p	Model
Crude model	0.06	0.08	0.455	R² = −0.002 p = 0.455
^b Adjusted model	0.08	0.09	0.368	R² = 0.077 p = 0.008
Anemia (0:no, 1:yes)	OR	95% CI	p	Model
Crude model	1.34	0.43–4.20	0.611	R² Nagelkerke = 0.004 p = 0.611
^a Adjusted model	1.02	0.20–5.10	0.984	R² Nagelkerke = 0.383 p = 0.007
Iron–deficiency anemia (0:no, 1:yes)	OR	95% CI	p	Model
Crude model	1.63	0.50–5.39	0.421	R² Nagelkerke = 0.010 p = 0.417
^a Adjusted model	1.02	0.20–5.10	0.984	R² Nagelkerke = 0.383 p = 0.007
Hemoconcentration (0:no, 1:yes)	OR	95% CI	p	Model
Crude model	0.46	0.20–1.06	0.068	R² Nagelkerke = 0.035 p = 0.061
^a Adjusted model	0.25	0.07–0.85	0.027	R² Nagelkerke = 0.261 p = 0.001

a Adjusted for: iron supplementation dosage, maternal age, use of hormonal contraception, pre–pregnancy maternal body mass index, gestational weight gain, HFE gene genotypes, maternal ethnic origin, hemoglobin on week 12, C–reactive protein on week 12, socioeconomic status, weekly mean of METS on week 12, smoking habit, alcohol intake, planned pregnancy, parity, mean caloric intake during pregnancy, and adherence to a Mediterranean diet. b Adjusted for: model a, except for hemoglobin on week 12.