miRNA | microRNA |
MDR | multi-drug-resistance |
PARP | poly adenosine diphosphate ribose polymerase |
PTEN | phosphatase and tensin homolog |
Akt | protein kinase B |
SHH | sonic hedgehog |
FLIP | cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein |
VEGF | vascular endothelial growth factor |
GM-CSF | granulocyte-macrophage colony-stimulating factor |
IL-12 | interleukin 12; KAI1, Kangai 1 |
OPG | osteoprotegerin; DNA, deoxyribonucleic Acid |
BAX | BCL2 Associated X |
LNCaP | lymph node carcinoma of the prostate |
ROS | reactive oxygen species |
NF-kB1 | nuclear factor kappa-light-chain-enhancer of activated B cells 1 |
HDAC3 | histone deacetylase 3 |
Puma | p53 upregulated modulator of apoptosis |
NOXA | NADPH oxidase activator |
JNK | Janus kinase |
MMP | mitochondrial membrane potential |
RIPK1 | receptor-interacting serine/threonine-protein kinase 1 |
Bcl-2 | B-cell lymphoma 2 |
Bim | Bcl-2-like protein 11 |
FADD | Fas-associated protein with death domain |
TRAIL | TNF-related apoptosis inducing ligand |
BITC | 3-butenyl isothiocyanate |
IC50 | the half maximal inhibitory concentration |
NK-kB | nuclear factor kappa light chain enhancer of activated B cells |
MTA1 | metastasis-associated protein 1 |
STAT3 IHC |
signal transducer and activator of transcription 3 Immunohistochemistry |
LLDT-288 | (14S)-14β-(1-(2-morpholinoethyl)-1H-indazol-5-ylamino)mthylepitriptolide |
ECM | extra-cellular matrix; EMT, epithelial-to-mesenchymal transition |
TRAMP | transgenic adenocarcinoma of mouse prostate |
NE-Ca | N-ethylcarboxamideadenosine |
PLA2 | phospholipases A2; COX, cyclooxygenase |
AA | acetic acid |
CXCR4 | C-X-C chemokine receptor type 4 |
PI3K | phosphoinositide 3-kinases |
CXCL12, | C-X-C motif chemokine ligand 12 |
MRP1 | multidrug resistance-associated protein 1 |
GSTπ | glutathione S-transferase Pi |
GST | glutathione S-transferase |
PPV | personalized peptide vaccination |
Mo-MDSC | monocytic myeloid-derived suppressor cells |