Table 2.
Pharmacokinetic parameters of choline.
| Variable | Mean 1 | 95% CI 1 | p-Value 2 |
|---|---|---|---|
| AUC0–12 h ((µmol/L)*h) (SB) | 26.07 | 19.72–32.42 | 0.2966 |
| AUC0–12 h ((µmol/L)*h) (CB) | 23.28 | 13.61–32.95 | |
| AUC0–24 h ((µmol/L)*h) (SB) | 29.57 | 21.26–37.87 | 0.4144 |
| AUC0–24 h ((µmol/L)*h) (CB) | 30.36 | 12.88–47.85 | |
| Cmax (µmol/L) (SB) | 4.21 | 3.43–4.99 | 0.2690 |
| Cmax (µmol/L) (CB) | 3.67 | 2.82–4.51 | |
| Tmax (h) (SB) | 4.17 | 2.9–5.43 | 0.0076 |
| Tmax (h) (CB) | 2.67 | 2.04–3.29 |
Abbreviations: SB: SuperbaBoostTM; CB: choline bitartrate; CI: confidence interval; AUC: area under the curve; Cmax: peak concentration; Tmax: time to reach maximum concentration. 1 Dose-adjusted values; 2 Difference between study products SB and CB.