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Pharmacokinetic parameters of betaine.
| Variable | Mean | 95% CI | p-Value 1 |
|---|---|---|---|
| AUC0–12 h ((µmol/L)*h) (SB) | 185.8 | 154–217.6 | 0.0641 |
| AUC0–12 h ((µmol/L)*h) (CB) | 168.4 | 137.4–199.4 | |
| AUC0–24 h ((µmol/L)*h) (SB) | 317.1 | 255.3–378.9 | 0.2394 |
| AUC0–24 h ((µmol/L)*h) (CB) | 286.9 | 229.0–344.8 | |
| Cmax (µmol/L) (SB) | 22.55 | 18.62–26.48 | 0.0122 |
| Cmax (µmol/L) (CB) | 18.87 | 15.31–22.42 | |
| Tmax (h) (SB) | 7.67 | 6.93–8.40 | 1.0 |
| Tmax (h) (CB) | 7.67 | 6.36–8.98 |
1 Difference between study products SB and CB.
