Table 5.

Pharmacokinetic parameters of TMAO.

Variable	Mean	95% CI	p-Value 1
AUC0–12 h ((µmol/L)*h) (SB)	10.06	4.19–15.92	<0.0001
AUC0–12 h ((µmol/L)*h) (CB)	104.3	59.8–148.8
AUC0–24 h ((µmol/L)*h) (SB)	25.41	11.76–39.06	<0.0001
AUC0–24 h ((µmol/L)*h) (CB)	288.3	231.8–362.8
Cmax (µmol/L) (SB)	2.24	1.17–3.30	<0.0001
Cmax (µmol/L) (CB)	28.99	20.36–37.63
Tmax (h) (SB)	12.0	9.35–14.65	0.7884
Tmax (h) (CB)	11.67	8.91–14.42

¹ Difference between study products SB and CB.