Table 1.

Summary statistics of changes in ERG components during light adaptation. All data shown in Figure 1C and Figure 2C were tested with a Friedmann-test, which considers all measured time points, while the animal was light adapted. Significance levels were corrected via the Bonferroni method: α_Bonferroni = 0.005. p-values that were below this significance level are highlighted.

ERG Component		Protocol	% Change During Light Adaptation Mean ± SD	p-Value
b-wave	amplitude [µV]	25 cd/m2	+21.8 ±18.8	<0.0005
		40 cd/m2	+22.3 ± 22.4	0.007 1
	implicit time [ms]	25 cd/m2	−7.7 ± 4.2	<0.0005
		40 cd/m2	−4.8 ± 1.8	<0.0005
PhNR	amplitude [µV]	25 cd/m2	+85.2 ± 116.0	0.007 1
		40 cd/m2	+47.5 ± 228.1	0.766
	implicit time [ms]	25 cd/m2	−8.5 ± 12.5	0.722
		40 cd/m2	+5.6 ± 13.3	0.722
2nd oscillatory potential (OP) peak	amplitude [µV]	25 cd/m2	+101.6 ± 103.9	0.453
		40 cd/m2	+133.9 ± 184.2	0.066
	implicit time [ms]	25 cd/m2	−1.7 ± 1.7	0.002
		40 cd/m2	−1.2 ± 2.2	0.140
3rd OP peak	amplitude [µV]	25 cd/m2	+70.6 ± 57.9	<0.0005
		40 cd/m2	+102.9 ± 127.7	0.017 1
	implicit time [ms]	25 cd/m2	−5.3 ± 1.8	<0.0005
		40 cd/m2	+0.7 ± 2.5	0.002
all OP (FFT analysis)	amplitude [µV]	25 cd/m2	+40.8 ± 47.4	0.008 1
		40 cd/m2	+29.2 ± 25.1	0.131

¹ p-value was not significant after Bonferroni correction for multiple testing.Highlighted p-values are below significance level.