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. 2019 Oct 21;11(10):2537. doi: 10.3390/nu11102537

Table 5.

The results of the analysis of the physico-chemical properties of selected antidiabetic peptides.

Peptide Molecular Weight
(gmol−1)
Isoelectric Point Net charge Solubility a Bioactivity Score b Peptide Molecular Weight
(gmol−1)
Isoelectric Point Net Charge Solubility a Bioactivity Score b
AF 236.27 3.77 0 - 0.97 NR 288.30 10.42 1 + 0.26
AL 202.25 3.70 0 - 0.44 NY 295.29 3.24 0 - 0.22
AW 275.30 3.66 0 - 0.97 PL 228.29 4.08 0 - 0.81
AY 252.27 3.66 0 - 0.35 PF 262.30 4.15 0 - 0.99
DG 190.15 0.68 −1 + 0.39 PK 243.30 10.57 1 + 0.33
DR 289.29 6.68 0 + 0.29 PW 301.34 4.04 0 - 0.99
EK 275.30 6.85 0 + 0.02 PY 278.30 3.85 0 - 0.74
EW 333.34 0.88 −1 + 0.59 SF 252.27 3.43 0 - 0.95
EY 310.30 0.95 −1 + 0.07 SK 233.27 9.86 1 + 0.07
GF 222.24 3.70 0 - 0.99 SL 218.25 3.37 0 - 0.33
GL 188.22 3.63 0 - 0.81 SY 268.27 3.39 0 - 0.26
GY 238.24 3.61 0 - 0.74 SW 219.30 3.34 0 - 0.93
HF 302.33 7.56 0 - 0.95 TF 266.29 3.36 0 - 0.83
HL 268.31 7.56 0.1 - 0.37 TK 247.29 9.28 1 + 0.03
HR 311.34 10.59 1.1 + 0.33 TL 232.28 3.32 0 - 0.14
HW 341.36 7.56 0.1 - 0.95 TR 275.31 10.53 1 + 0.13
HY 318.33 7.54 0.1 - 0.30 TY 282.29 3.35 0 - 0.11
IL 244.33 3.64 0 - 0.39 QF 293.32 3.41 0 - 0.95
IR 287.36 10.85 1 + 0.33 QL 259.30 3.34 0 - 0.29
IW 317.38 3.61 0 - 0.94 QY 309.32 3.36 0 - 0.23
MF 296.39 3.45 0 - 1.00 VF 264.32 3.67 0 - 0.82
MK 277.39 9.88 1 + 0.45 VK 245.32 10.10 1 + 0.03
ML 262.37 3.38 0 - 0.89 VL 230.30 3.60 0 - 0.13
MR 305.40 10.59 1 + 0.85 VR 273.33 10.10 1 + 0.11
MW 335.42 3.35 0 - 1.00 VW 303.36 3.57 0 - 0.80
NF 279.29 3.28 0 - 0.94 VY 280.32 3.59 0 - 0.10
NL 245.28 3.21 0 - 0.29 VPL 327.42 3.60 0 - 0.37

a Estimated solubility in water where “+” means good solubility and “-” means poor solubility; b bioactivity score obtained with PeptideRanker tools.