Figure 1.

Study design. After a transient occlusion of the middle cerebral artery (tMCAo) for 30 min, mice were divided into two dietary groups (Control or HT-enriched). At seven and 35 days post-tMCAo, all mice underwent Magnetic Resonance Imaging (MRI). In between, all mice were tested on motor and cognitive impairments via several behavioral tests, like the Open field, Rotarod, Pole test, Prepulse inhibition (Ppi), grip strength test, and novel object recognition test (ORT). After MRI at day 35, animals were sacrificed, serum samples were recollected, and all brains were processed for immunohistochemical stainings and qPCR analysis.