Figure 5.

Grip strength in the forelimbs (trapeze) and in all four paws (grid) before (pre) and after (weeks 2 and 4) stroke. (A) Time effects and (B) diet effects on maximum grip strength are shown. (A) At week 2, sham mice showed a lower grip strength on the grid compared to pre-surgery (p < 0.004). A surgery effect was observed at week 2, shown by weaker grip strength in forelimbs in stroke-control mice compared to sham-control mice (p < 0.002). At four weeks post-surgery, sham mice showed a decreased forelimb grip strength compared to two weeks post-surgery (p < 0.001). (B) HT-fed stroke mice demonstrated a higher grip strength on the trapeze at weeks 2 and 4 compared to stroke control diet-mice (p < 0.018). Values represent mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001.