Table 2.
Linearity, limit of quantification and inter-assay variation.
| Metabolite (a) | Linearity (µmol/L) | LoQ (µmol/L) | Inter-assay Variation (%) |
|---|---|---|---|
| Cysteine | 0–300 | 0.9 | 2.95 |
| Cystine | 0–100 | 0.04 | 11.22 |
| Homocysteine | 0–100 | 0.35 | 4.86 |
| Homocystine | 0–50 | 0.02 | 10.2 |
| Glutathione | 0–20 | 0.05 | 2.56 |
| Glutathione disulfide | 0–20 | 0.63 | 7.57 |
| Methionine | 0–150 | 1.65 | 3.74 |
| Methionine sulfoxide | 0–150 | 0.08 | 3.73 |
| Cystathionine | 0–50 | 0.01 | 2.64 |
| Creatinine | 0–500 | 0.01 | 2.35 |
(a) Linearity, limit of quantification and inter-assay variation for derivatized versions of Cys, Hcy and GSH did not differ from those of their corresponding parent metabolite.