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. 2019 Nov 6;20:244. doi: 10.1186/s12931-019-1216-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Proportions of circulating Breg cells in IPF and healthy cases. a Representative fluorescence-activated cell sorting profiles indicating Breg cells (CD24^hiCD27⁺). Plots were pregated on CD3⁻CD19⁺ cells and examined according to the levels of CD24 and CD27. The numbers indicate the proportion of cells in the gate. b The proportion of Breg cells among all CD3⁻CD19⁺ B cells is shown in the panel. Breg, regulatory B; IPF, idiopathic pulmonary fibrosis