Table 5.
Regions of reduced heterozygosity (RORH) in Djallonke and Sahelian sheep co-localised with reported candidate genes for resistance to nematodes
| Sheep breed | Genomic region (bp) co-localised with RORH (Oar_v3.1) | Candidate Gene | Trait Inference | Reference |
|---|---|---|---|---|
| Both | 20:25,400,738-25,402,966 | MHCII-DRB1 | Gastrointestinal nematodes | Schwaiger et al. (1995) |
| Djallonke | 1:27,524,283-27,601,025 | LRP8 | H. contortus | Benavides et al. (2016) |
| Djallonke | 1:87,657,990-87,674,113 | DENND2D | H. contortus | McRae et al. (2014) |
| Djallonke | 1:87,710,082-87,728,410 | CHI3L2 | H. contortus | McRae et al. (2014) |
| Djallonke | 1:87,788,905-87,811,255 | CHIA | H. contortus | McRae et al. (2014) |
| Djallonke | 3:151,527,165-151,535,188 | IFNG | Mixed intestinal parasites | Coltman et al., 2001 |
| Djallonke | 3:123,851,175-125,982,479 | ATP2B1 | H. contortus | Benavides et al. (2016) |
| Djallonke | 8:62,006,022-62,039,859 | IL20RA | H. contortus + others | Periasamy et al., 2014 |
| Both | 12:41,923,922-41,973,979 | PIK3CD | H. contortus + others | Periasamy et al., 2014 |
| Djallonke | 12:62,163,057-62,283,591 | LAMC1 | H. contortus | Benavides et al. (2016) |
| Both | 15:55,404,807-55,417,235 | MUC15 | H. contortus | Benavides et al. (2016) |
| Djallonke | 17:52,168,248-52,191,479 | ABCB9 | H. contortus | Yang et al., 2015 |
| Djallonke | 10:11,465,154-11,505,274 | SUGT1 | H. contortus | Yang et al., 2015 |
| Djallonke | 14:48,062,306-48,071,138 | PAK4 | H. contortus | Yang et al., 2015 |
| Djallonke | 14:14,206,784-14,215,316 | FCER2 | H. contortus | Yang et al., 2015 |
| Djallonke | 4:44,668,137-45,205,142 | RELN | H. contortus | McRae et al., 2014 |
| Djallonke | 6:89,053,717-89,061,196 | AREG | H. contortus | Zhengyu et al., 2016 |
| Djallonke | 11:57,796,766-57,800,093 | SOX9 | H. contortus | Benavides et al., 2016 |
| Djallonke | 6:70,189,729-70,234,612 | KIT | H. contortus | Zhengyu et al., 2016 |
| Djallonke | 16:66,450,575-66,482,861 | NSUN2 | H. contortus | McRae et al., 2014 |
| Both | 19:47,044,394-47,059,322 | IL17RB | H. contortus | Zhengyu et al., 2016 |
| Djallonke | 19:55,173,564-55,175,033 | HRH1 | H. contortus | McRae et al., 2014 |
| Djallonke | 25:44,535,996-44,543,183 | CXCL12 | H. contortus | Zhengyu et al., 2016 |
| Djallonke | 19:53,290,059-53,291,096 | CXCR6 | H. contortus | Zhengyu et al., 2016 |
| Djallonke | 20:34,055,201-34,055,659 | UBE2N | H. contortus | Benavides et al., 2016 |