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. 2019 Nov 6;19:278. doi: 10.1186/s12935-019-1000-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Volcano plot of differentially expressed genes in CRC and expression profiling of SATB1-AS1 in patient samples. a Volcano plot of differentially expressed genes (p < 0.001) in tumoral versus adjacent mucosal colorectal adenocarcinoma samples. The horizontal axis shows the log2 fold up-regulation (to the right) and down-regulation (to the left) in the expression of genes. The vertical axis demonstrates negative log10 of the p-value of Fisher’s exact test. Each gene is represented by one circle on the graph. Red circles represent genes that are significantly de-regulated. b Quantified expression of SATB1-As1 in the polyp/tumoral tissue in comparison with normal tissue in patients with low-grade adenoma, advanced adenoma, and adenocarcinoma