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. 2019 Nov 6;20(1):101. doi: 10.1186/s10194-019-1050-8

Table 5.

Burden of headache, acute medication use and health-related quality of life by headache diagnosis (N = 2562)

No headache (n = 824) UdH (n = 884) All migraine (n = 821) All TTH (n = 731) H15+ (n = 101) Test statistic, p-valuef
Headache burden (reported at least once in previous 4 weeks) (% of participants)
 Headache-attributed lost time:
  Missed whole school day 11.0%a 20.5%b 11.3%a 31.3%c Chi2 = 47.3, p < 0.001
  Left school early 7.6%a 15.2%b 9.0%a 24.2%c Chi2 = 35.6, p < 0.001
  Missed other activities 26.8%a 57.3%b 34.5%c 60.2%b Chi2 = 141.6, p < 0.001
 School performance (mean, SD)e 2.1 (0.8)a, b 2.1 (0.8)a 2.3 (0.8)b 2.2 (0.8)a, b 2.3 (0.90)b F = 6.7, p < 0.001
Acute medication use in previous 4 weeks
 Participants (%) 28.5a 58.7b 43.9c 67.3b Chi2 = 128.9, p < 0.001
 Number of days (mean, SD) 0.8 (2.5)a 1.8 (2.6)b 1.0 (1.7)a 6.5 (7.6)c F = 121.4, p < 0.001
Health-related quality of life (HrQoL)
 Overall HrQoL 52.9 (10.8)a 53.9 (9.5)a 47.5 (11.2)b 50.6 (10.4)c 43.1 (11.9)d F = 56.3, p < 0.001
  Self-perception 51.0 (9.7)a 50.9 (9.2)a 46.4 (10.0)b 48.2 (9.9)b 42.9 (10.8)c F = 42.3, p < 0.001
  Parent-relation and home life 53.9 (9.2)a 53.6 (8.7)a 50.3 (11.1)b 51.9 (9.7)a, b 44.8 (13.9)c F = 31.6, p < 0.001
  Social support and peers 52.6 (9.4)a 53.1 (8.7)a 51.6 (9.8)a 52.1 (8.8)a 49.6 (13.2)b F = 4.8, p = 0.001
  School environment 52.7 (10.5)a, c 53.4 (8.8)a 48.4 (10.1)b 50.9 (9.3)c 45.6 (12.6)d F = 39.5, p < 0.001
  Bullying 50.7 (10.6)a 51.9 (8.9)a 50.4 (10.2)a 50.7 (9.7)a 47.3 (14.3)b F = 6.4, p < 0.001

UdH Undifferentiated headache, TTH Tension-type headache, H15+ Headache on ≥15 days/month. a,b,c,dThese superscript notations indicate groups differing significantly on Tukey post-hoc analyses. eOn scale 1–4 where 1 = very good, 4 = below average (see text). fBonferroni corrections applied to significance values to adjust for multiple comparisons of headache burden measures (p = 0.013) and of HrQoL measures (p = 0.008)