Table 5.
Predictors of bacterial co-infection
| Negative (N = 37) | Co-infection (N = 63) | Low Bacterial Growth (N = 67) | P Value** univariate | P Value** Multivariate | |
|---|---|---|---|---|---|
| Age (months) | 4.1 ± 5.2 | 2.3 ± 2.6 | 3.0 ± 3.4 | 0.053 | 0.088 |
| Fever (> 38,5 °C) | 0 (0.0%) | 3 (4.8%) | 1 (1.5%) | 0.394 | |
| CRP (mg/l)* | 57.6 ± 53.8 | 97.7 ± 51.8 | 102.6 ± 69.5 | < 0.001 | 0.001 |
| CRP 0–40 mg/l | 21 (56.8%) | 9 (14.3%) | 12 (17.9%) | < 0.001 | |
| 40–100 mg/l | 9 (24.3%) | 28 (44.4%) | 23 (34.3%) | ||
| > 100 mg/l | 7 (18.9%) | 26 (41.3%) | 32 (47.8%) | ||
| Leukocytes* (10e9/ml)* | 12.58 ± 4,72 | 14.67 ± 7.25 | 14.16 ± 6.79 | 0.085 | – |
| Neutrophils* (10e9/ml)* | 6.38 ± 4,45 | 8.93 ± 6.50 | 8.40 ± 6.41 | 0.048 | – |
| Two viral infections | 4/21 (19.0%) | 6/23 (26.1%) | 12/43 (27.9%) | 0.578 | |
| CXR*** Consolidation | 15/36 (19.0%) | 25/62 (40.3%) | 33/66 (50.0%) | 0.896 | |
| Antibiotics before 1st culture | 9/34 (75.0%) | 21/59 (35.6%) | 39/63 (61.9%) | < 0.001 | 0.000 |
* maximum value
** negative vs co-infection;- participated in the multivariate analysis, but removed
*** chest x-ray