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. 2019 Nov 6;19:1056. doi: 10.1186/s12885-019-6291-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — PRMT5 expression and correlation in primary medulloblastomas. a Boxplots showing PRMT5 expression in five non-overlapping cohorts (total n = 491) of medulloblastoma tumors compared to normal cerebellum (n = 9) controls. *Anova p < 0.05 vs. medulloblastoma. b PRMT5 expression in four (Group3, Group 4, SHH and WNT) medulloblastoma subgroups using Pfister (n = 223) cohort dataset. *Anova p < 0.05 vs. Group 3. Kaplan-Meier plots showing overall survival of patients (Cavalli 763 cohort) with medulloblastoma all subgroups (c) and Group 3 medulloblastoma (d) with respect to PRMT5 expression