Table 4.
Baseline characteristics of patients with oral and laryngeal SCC
| Oral SCC (n = 260) | Laryngeal SCC (n = 134) | |
|---|---|---|
| Male : Female | 151:109 | 127:07 |
| Age (years) | ||
| Mean | 61.3 | 63.4 |
| Range | 29-95 | 36-89 |
| Surgery : Biopsy | 133:127 | 49:85 |
| Site | ||
| lip, n =18 | supraglottic, n = 34 | |
| oral tongue, n =159 | glottic, n = 6 | |
| floor mouth, n = 27 | subglottic, n = 3 | |
| buccal, n = 21 | transglottic, n = 71 | |
| alveolar ridge, n =18 | not specified, n = 20 | |
| hard palate, n = 8 | ||
| retromolar trigone, n = 9 | ||
| Grade | ||
| Well-differentiated | 149 | 57 |
| Moderately-differentiated | 105 | 68 |
| Poorly-differentiated | 6 | 9 |
| p16-positive | 9 | 6 |
| HPV ISH-positive | 10* | 2** |
| p16+/HPV ISH+ | 4 (1.5%) | 2 (1.5%) |
* out of 156 tested with ISH
** out of 7 tested with ISH
SCC squamous cell carcinoma, HPV human papilloma virus, ISH DNA in situ hybridization