Table 2.
Uni- and multivariable analysis for LNM/LVI of EGC patients in the training set
| Parameters | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|
| Odds Ratio (95%CI) | P-value | Odds Ratio (95%CI) | P-value | |
| Age | ||||
| ≤ 60 | Ref | |||
| > 60 | 0.997 (0.776–1.282) | 0.984 | ||
| Sex | ||||
| Male | Ref | Ref | ||
| Female | 1.476 (1.135–1.92) | 0.004 | 1.492 (1.134–1.963) | 0.004 |
| Tumor location | 0.714 | |||
| Upper | Ref | |||
| Middle | 1.117 (0.765–1.63) | 0.568 | ||
| Lower | 1.001 (0.695–1.443) | 0.994 | ||
| Overlapa | 1.28 (0.739–2.217) | 0.378 | ||
| Tumor size | ||||
| ≤ 20 mm | Ref | Ref | ||
| > 20 mm | 1.73 (1.346–2.224) | < 0.001 | 1.536 (1.184–1.992) | 0.001 |
| Depth of invasion | ||||
| Mucosa | Ref | Ref | ||
| Submucosa | 2.939 (2.22–3.892) | < 0.001 | 2.898 (2.177–3.858) | < 0.001 |
| Tumor histological types | ||||
| Differentiated | Ref | Ref | ||
| Undifferentiated | 2.03 (1.52–2.71) | < 0.001 | 1.983 (1.474–2.668) | < 0.001 |
Abbreviations: Ref reference, CI confidence interval, LVI lymphovascular invasion, EGC early gastric cancer, LNM lymph node metastasis
aOverlap, tumor invaded two or more regions simultaneously