Table 2.

Effects of increasing age and different treatments on the body weights (g) of ICR mice

Group	Week
	0	1	2	3	4	5	6	7
Normal control	21.26 ± 1.18	26.60 ± 1.57	29.50 ± 1.02	32.32 ± 1.30	36.33 ± 1.25	38.34 ± 1.57	40.08 ± 1.60	42.77 ± 1.15
Model control	21.49 ± 1.24	26.59 ± 2.62	29.74 ± 1.28	32.40 ± 1.14	36.51 ± 1.32	35.68 ± 1.65d	35.04 ± 0.92d	34.19 ± 1.16d
Positive control	21.38 ± 1.05	26.77 ± 1.11	28.41 ± 1.67	32.33 ± 2.23	35.99 ± 2.62	36.54 ± 1.59ac	39.02 ± 2.39b	41.59 ± 2.92b
RIP (25 mg/kg)	21.26 ± 0.75	26.08 ± 1.43	27.67 ± 1.24ac	31.08 ± 1.57	33.86 ± 2.47ac	36.14 ± 2.42ac	38.00 ± 2.84bc	40.65 ± 1.25b
RIP (50 mg/kg)	21.56 ± 0.69	26.26 ± 0.85	30.85 ± 1.27	32.18 ± 0.84	35.54 ± 2.38	37.83 ± 2.89c	38.63 ± 3.06bc	40.12 ± 3.01b
RIP(100 mg/kg)	21.12 ± 1.43	26.82 ± 1.09	31.16 ± 1.24	33.73 ± 1.91	36.79 ± 1.57	37.81 ± 2.47c	38.27 ± 2.98bc	41.12 ± 2.16b

Results are given as mean body weights ± standard deviation (S.D.) (n = 10) and evaluated by one-way ANOVA followed by the Duncan’s multiple-range tests. Differences were considered to be statistically significant if P < 0.05

^a P < 0.05, compared with model group

^b P < 0.01, compared with model group

^c P < 0.05, compared with normal group

^d P < 0.01, compared with normal group